![]() ![]() Liver function tests are used to see how well your liver works. ![]() This side effect usually needs treatment in a hospital. Some possible symptoms include severe muscle pain, dehydration, and red or brown urine. If it happens, it can cause intense muscle breakdown and even damage to your kidneys. This is one of the most serious side effects of statins, but it is very rare. They can help you treat it and possibly change medications, so it does not continue to occur. Let your healthcare provider know if you experience this side effect, especially if it’s bothersome or doesn’t go away. Muscle painĪlso called myalgia, this is the most common statin side effect. Here are some side effects of statins you should be aware of, and what to do about it if they happen. There are many possible side effects of statin medications, but most of them tend to be mild. The side effects that could occur are simply more likely to happen and/or be worse. Since the only effect that grapefruit and grapefruit juice have on some statins is to raise the level of statins in the body, there aren’t any “new” side effects that occur when the two are mixed. Side effects of mixing grapefruit and statins For example, one study found that there were improvements in LDL cholesterol reduction and a slightly lower risk of heart disease from taking atorvastatin, simvastatin, or lovastatin with grapefruit juice. On the other hand, higher statin levels can also boost their cholesterol-lowering effects. These side effects are more likely to happen if you consume large amounts of grapefruit or grapefruit juice. Although it’s rare, serious side effects like rhabdomyolysis are also possible. When this happens, it may cause unpleasant and even harmful side effects, like muscle pain (also known as myalgia). As a result, those statins stay active in the body for longer than expected. In the case of certain statins, grapefruit chemicals stop them from being broken down. In essence, grapefruit chemicals can affect how those enzymes process medications. Coincidentally, the chemicals in grapefruit can affect the enzymes that break down some statins. Your liver contains enzymes (proteins) that break down foods and medications so they can be eliminated from your body. How does grapefruit interact with statins? Here’s what you need to know about grapefruit and statins. Has your healthcare provider ever warned you to avoid eating grapefruit or drinking grapefruit juice if you’re taking a statin medication to treat high cholesterol? It might seem like a strange association, but certain statins, such as atorvastatin (Lipitor) and simvastatin (Zocor), can interact with grapefruit and grapefruit juice, raising your risk for harmful side effects. ![]()
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